教育和工作经历

2019-至今，澳门永利唯一官网304，教授

2016-2018，美国University of Florida，博士后（导师：谭蔚泓教授）

2010-2016，美国University of Massachusetts Amherst，博士 （导师：Vincent M. Rotello教授）

研究领域

分析化学；电化学；脑神经分析化学；纳米生物化学；化学生物学

研究兴趣

本实验室主要围绕脑神经分析化学领域展开工作。以活动物脑内神经化学信号分子为对象，通过创新分析化学原理和方法，实现对于神经生理和病理过程中神经化学信号的精准测量。主要包括以下三方面工作：1）构建具有高选择性和高稳定性的活体识别元件；2）发展多通道活体分析方法；3）探索神经信号分子在大脑活动尤其是神经退行性疾病过程的作用机制。

招生信息

每年招收博士生1-2名，硕士生1-2名。同时招收博士后。 具有化学、生物和材料等研究背景者优先。

代表性论文

1.       Zhu, F.; Xue, Y.; Ji, W.; Li, X.; Ma, W.; Yu, P.; Jiang, Y.;*, and Mao, L.* Galvanic Redox Potentiometry for Fouling-Free and Stable Serotonin Sensing in a Living Animal Brain. Angew. Chem. Int. Ed., 2023, e202212458.
2.        Li, X.; Jin, Y.; Zhu, F.; Liu, R.; Jiang, Y.; Jiang, Y.;*, and Mao, L.* Electrochemical Conjugation of Aptamers on Carbon Fiber Microelectrode Enables Highly Stable and Selective In Vivo Neurosensing. Angew. Chem. Int. Ed., 2022, 61, e202208121.
3.         Jin, J.; Mao, J.; Wu, W.; Jiang, Y.;*, Ma, W.; Yu, P.; Mao, L.* Highly Efficient Electrosynthesis of Nitric Oxide for Biomedical Applications, Angew. Chem. Int. Ed., 2022, 61, e2022109.
4.       Xue, Y.; Ji, W.; Jiang, Y.;*, Yu P.; and Mao L.* Deep Learning for Voltammetric Sensing in a Living Animal Brain, Angew. Chem. Int. Ed., 2021, 60, 23777–23783.
5.       Hou, H.; Jin, Y.; Wei, H.; Ji, W.; Xue, Y.; Hu, J.; Zhang, M.; Jiang, Y.;* and Mao, L.* A Generalizable and Noncovalent Strategy of Interfacing Aptamers with Microelectrode for Selective Sensing of Neurotransmitter In Vivo, Angew. Chem. Int. Ed., 2020, 59, 18996-19000.
6.       Jin, J.; Ji, W.; Li, L.; Zhao, G.; Wu, W.; Wei, H.; Ma, F.; Jiang, Y.;* and Mao, L.* Electrochemically Probing Dynamics of Ascorbate during Cytotoxic Edema in Living Rat Brain, J. Am. Chem. Soc., 2020, 142, 19012-19016.
7.     Xiao, T.; Wang, Y.; Wei, H.; Yu, P.; Jiang, Y.;* and Mao, L.* Electrochemical Monitoring of Propagative Fluctuation of Ascorbate in the Live Rat Brain during Spreading Depolarization, Angew. Chem. Int. Ed., 2019, 58, 6616–6619.
8.     Jiang, Y,; Pan, X.; Chang, J.; Niu, W. J.; Hou, W. J.; Kuai, H.; Zhao, Z.; Liu, J.; Wang, M.; and Tan, W. Supramolecularly Engineered Circular Bivalent Aptamer for Enhanced Functional Protein Delivery, J. Am. Chem. Soc., 2018, 140, 6780-6784.
9.        Jiang, Y.; Shi, M.; Liu, Y.; Wan, S.; Cui, C.; Zhang, L.; and Tan, W. Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins, Angew. Chem. Int. Ed., 2017, 56, 11916-11920.
10.     Jiang, Y.; Tang, R.; Duncan, B.; Jiang, Z. W.; Yan, B.; Mout, R.; and Rotello, V. M. Direct Cytosolic Delivery of siRNA Using Nanoparticle Stabilized Nanocapsules, Angew. Chem. Int. Ed., 2015, 54, 506-510.